Set 2: Command of Evidence (Advanced)

Explanation

Answer: A

PASSAGE

CRISPR allows precise gene editing. However, off-target effects (unintended edits) remain a concern. Recent studies show improved guide RNA designs reduce off-target rates.

What challenge does CRISPR still face?

A. It cannot edit genes.✓ Correct

B. Unintended edits elsewhere in the genome.

C. It is too expensive to produce.

D. Guide RNAs don't work.

Detailed Explanation

This question requires you to identify evidence that supports a claim. 'Off-target effects (unintended edits) remain a concern.' The best evidence directly and explicitly supports the stated claim without requiring assumptions. Match specific textual details or data points to the claim being made. The correct answer provides clear, direct support. Strong evidence directly addresses the claim without requiring additional interpretation. When evaluating options, look for quotes or data that explicitly support the statement. Weak evidence may be tangentially related but doesn't provide direct proof.

Key Evidence:

• "CRISPR allows precise gene editing"

• "However, off-target effects (unintended edits) remain a concern"

Why others are wrong: B (This option is incorrect.), C (This option is incorrect.), D (This option is incorrect.).

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