Set 1: Command of Evidence (Advanced)
Explanation
PASSAGE
Epigenetics involves changes in gene expression that do not involve alterations to the DNA sequence. Methylation is a common mechanism where a methyl group attaches to DNA, typically repressing gene transcription. Researchers found that mice exposed to high stress showed increased methylation in genes regulating stress response.
What is the likely functional consequence of the increased methylation observed in the mice?
Detailed Explanation
This question requires you to identify evidence that supports a claim. The text states methylation 'typically repressing gene transcription'. Transcription leads to protein production. If transcription is repressed (reduced), then protein production is reduced. The best evidence directly and explicitly supports the stated claim without requiring assumptions. Match specific textual details or data points to the claim being made. The correct answer provides clear, direct support. Strong evidence directly addresses the claim without requiring additional interpretation. When evaluating options, look for quotes or data that explicitly support the statement. Weak evidence may be tangentially related but doesn't provide direct proof.
Key Evidence:
• "typically repressing gene transcription"
Why others are wrong: B (This option is incorrect.), C (Reduced stress response often makes stress *worse*, not immune.), D (Not mentioned.).