The new drug trial showed no significant side effects during the first three months. _______ nearly 15 percent of participants later reported experiencing severe headaches.
Which choice completes the text with the most logical transition?
Similarly,
Therefore,
In addition,
Unexpectedly,
Correct Answer: D
Choice D is the best answer. This question tests transitions indicating unexpected results.
- Context clues: Initial findings were positive; later results contradicted expectations.
- Meaning: Unexpected outcomes use "unexpectedly," "surprisingly," "contrary to expectations."
- Verify: "Unexpectedly, nearly 15 percent" signals the surprising later development.
💡 Strategy: When results contradict expectations or initial findings, use surprise transitions (unexpectedly, surprisingly).
Choice A is incorrect because headaches don't "similarly" follow from no side effects. Choice B is incorrect because headaches aren't a logical consequence of no side effects. Choice C is incorrect because "In addition" suggests the headaches add to, not contradict, the earlier finding.